Jean-Marc Egly Selected Research

Cockayne Syndrome (Syndrome, Cockayne)

12/2020	The Cockayne syndrome group A and B proteins are part of a ubiquitin-proteasome degradation complex regulating cell division.
6/2013	Regulatory interplay of Cockayne syndrome B ATPase and stress-response gene ATF3 following genotoxic stress.
5/2013	Cockayne syndrome group B (CSB) protein: at the crossroads of transcriptional networks.
1/2013	Sirt1 suppresses RNA synthesis after UV irradiation in combined xeroderma pigmentosum group D/Cockayne syndrome (XP-D/CS) cells.
6/2010	A ubiquitin-binding domain in Cockayne syndrome B required for transcription-coupled nucleotide excision repair.
4/2007	XPG stabilizes TFIIH, allowing transactivation of nuclear receptors: implications for Cockayne syndrome in XP-G/CS patients.
8/2006	When transcription and repair meet: a complex system.
5/2006	Cockayne syndrome B protein regulates the transcriptional program after UV irradiation.
7/2004	DNA damage stabilizes interaction of CSB with the transcription elongation machinery.

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Jean-Marc Egly Research Topics

Disease

9	Cockayne Syndrome (Syndrome, Cockayne) 12/2020 - 07/2004
9	Trichothiodystrophy Syndromes 01/2019 - 11/2002
7	Xeroderma Pigmentosum (Kaposi's Disease) 02/2015 - 09/2006
6	Neoplasms (Cancer) 01/2019 - 03/2011
3	Intellectual Disability (Idiocy) 12/2019 - 03/2008
2	DNA Repair-Deficiency Disorders (Chromosome Instability Syndromes) 01/2019 - 07/2004
2	Skin Neoplasms (Skin Cancer) 05/2014 - 08/2013
2	Hypoxia (Hypoxemia) 05/2013 - 03/2011
2	Inborn Genetic Diseases (Disease, Hereditary) 12/2009 - 11/2007
2	Microcephaly 03/2008 - 11/2007
1	Melanoma (Melanoma, Malignant) 01/2021
1	Lamellar Ichthyosis (Harlequin Ichthyosis) 03/2020
1	Genomic Instability 12/2018
1	Human Influenza (Influenza) 11/2016
1	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 10/2016
1	Hypersensitivity (Allergy) 01/2013
1	Nervous System Diseases (Neurological Disorders) 08/2011
1	Hepatocellular Carcinoma (Hepatoma) 03/2011
1	Cataract (Cataracts) 03/2008
1	Fever (Fevers) 02/2004
1	Infections 02/2004

Drug/Important Bio-Agent (IBA)

9	Transcription Factor TFIIHIBA 02/2015 - 11/2002
7	Proteins (Proteins, Gene)FDA Link 12/2020 - 07/2004
3	UbiquitinIBA 12/2020 - 06/2010
3	Phosphotransferases (Kinase)IBA 12/2019 - 02/2011
3	RNA (Ribonucleic Acid)IBA 11/2016 - 02/2004
3	DNA (Deoxyribonucleic Acid)IBA 10/2016 - 09/2006
3	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA 08/2013 - 04/2007
2	Proteasome Endopeptidase Complex (Proteasome)IBA 12/2020 - 10/2016
2	Pharmaceutical PreparationsIBA 10/2016 - 01/2014
2	RNA Polymerase II (RNA Polymerase B)IBA 10/2016 - 07/2004
2	Sirtuin 1IBA 10/2014 - 01/2013
2	A-Form DNA (A-DNA)IBA 11/2007 - 08/2006
1	CholesterolIBA 03/2020
1	Liver X ReceptorsIBA 03/2020
1	transcription factor TFIIE (TFIIE)IBA 01/2019
1	ChromatinIBA 01/2019
1	Nuclear Proteins (Protein, Nuclear)IBA 12/2018
1	Virulence Factors (Pathogenicity Factors)IBA 11/2016
1	PM 01183IBA 10/2016
1	Immunosuppressive Agents (Immunosuppressants)IBA 05/2014
1	PlatinumIBA 03/2014
1	SulfurIBA 08/2013
1	Sucrose (Saccharose)IBA 06/2013
1	Adenosine Triphosphatases (ATPase)IBA 06/2013
1	Insulin (Novolin)FDA Link 05/2013
1	Ribosomal DNA (rDNA)IBA 05/2013
1	Transcription Factors (Transcription Factor)IBA 02/2013
1	Cyclin-Dependent Kinase-Activating KinaseIBA 02/2013
1	Cyclin-Dependent Kinases (cdk Proteins)IBA 02/2013
1	Prothrombin (Factor II)IBA 02/2013
1	Histone MethyltransferasesIBA 01/2013
1	inositol trispyrophosphateIBA 03/2011
1	Oxygen (Dioxygen)IBA 03/2011
1	Hemoglobins (Hemoglobin)IBA 03/2011
1	Doxorubicin (Adriamycin)FDA LinkGeneric 03/2011
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 03/2011
1	Caspase 3 (Caspase-3)IBA 03/2011
1	Retinaldehyde (Retinal)IBA 03/2008
1	SolutionsIBA 04/2007

Therapy/Procedure

3	Therapeutics 01/2021 - 03/2011
1	Intravenous Injections 03/2011
1	Drug Therapy (Chemotherapy) 03/2011